[Home ] [Archive]    
:: Main About journal Editorial Board Current Issue Archive Submit an article Site Map Contact ::
Main Menu
Home::
Journal Information::
Articles archive::
For Authors::
For Reviewers::
Registration::
Contact us::
Site Facilities::
Editorial Board::
::
Search in website

Advanced Search
..
Receive site information
Enter your Email in the following box to receive the site news and information.
..
:: Volume 4, Issue 2 (June 2015) ::
Int J Med Invest 2015, 4(2): 252-256 Back to browse issues page
Oral Cephalosporin Cefodox for treatment of out patient pneumonia in children
Alaa Altawalbeh * , Thaer Almomani , Mohammed Shatnawi , Yazen Qawasmeh , Abdelkhaleq Al Shbool
Department of Pediatrics, Royal Medical Services. Amman .Jordan.
Abstract:   (9338 Views)
Objectives: to evaluate the efficacy and tolerability of the oral third generation cephalosporin Cefodox in the treatment of community-acquired pneumonia in children. Patients: the study was conducted in pediatric outpatient clinic at prince Rashid military hospital over six months from 1-09- 2013 to 28-02-2015. A total number of 270 children aged from1 to 14 year with diagnosis of chestinfections were included in the study. Patients who have any chronic illnesses, immunodeficiency or were taking any antibiotics within 5 days of diagnosis were excluded. Methods: according to the age, patients were divided into three age groups: first group with age 1-4 years, second group from 4-8 years and the third group 8 to 14years. Males to females ratio was (1.7:1).All patients were started on oral Cefodox twice daily for 10 days.Follow up was done for all patients at day 5 and day 10 after treatment.Chestradiograph was performed to all patients on day 10. Results: The efficacy of the drug Cefodox was evaluated by the change and improvement of the clinical symptoms, physical examination and chest radiograph.All children in all age groups and both sexes showed improvement in all parameters by day 10 without complications and significant drug reactions. Conclusion: Cefodox is effective, well tolerated and safe in the treatment of children with community-acquired pneumonia.
Keywords: Children, pneumonia, Cefodox.
Full-Text [PDF 347 kb]   (2534 Downloads)    
Type of Study: Research | Subject: General
References
1. 1. Garibaldi RA. Epidemiology of community-acquired respiratory tract infections in adults: incidence, aetiology, and impact. Am J Med 1985; 78: 32–37. 2. Donowitz GR, Mandell GL. Acute pneumonia. In: Mandell GL, Douglas RG, Benett JE, eds. Principles and Practice of Infectious Diseases. 4th Edn. New York, Churchill Livingstone, 1990; pp. 619–637. 3. Marrie TJ. Community-acquired pneumonia. Clin Infect Dis 1994; 18: 501–515. 4. Bartlett JG, Mundy LM. Community-acquired pneumonia. New Engl J Med 1995; 333: 1618–1624. 5. Fang GD, Fine M, Orloff J, et al. New and emerging aetiologies for community-acquired pneumonia with implications for therapy. A prospective multicenter study of 359 cases. Medicine 1990; 69: 307–316. 6. Mayaud C, Parrot A, Houacine S, Denis M, Akoun G. Epidémiologie des germes responsables des infections communautaires des voies respiratoires inférieures. Méd Mal Infect 1992; 2 (Suppl.): 130–139. 7. Woodhead MA, Macfarlane JT, McCracken JS, Rose DH, Finch RG. Prospective study of the aetiology and outcome of pneumonia in the community. Lancet 1987; i: 671–674. 8. Macfarlane JT, Colville A, Guion A, Macfarlane RM, Rose DH. Prospective study of aetiology and outcome of adult lower-respiratory-tract infections in the community. Lancet 1993; 341: 511–514. 9. Francioli P, Moser F. Epidémiologie des pneumonies diagnostiquées en pratique ambulatoire. Rev Méd Suisse Romande 1992; 112: 337–339. 10. Pomilla PV, Brown RB. Outpatient treatment of community-acquired pneumonia in adults. Arch Intern Med 1994; 154: 1793–1802. 11. Klugman KP. Pneumococcal resistance to antibiotics. Clin Microbiol Rev 1990; 3: 171–176. 12. British Thoracic Society Research Committee. Community acquired pneumonia in adults in British hospitals in 1982–1983: a survey of aetiology, mortality, prognostic factors and outcome. Q J Med 1987; 62: 195–200. 13. MacFarlane J, Ward MJ, Finch RG, Macrae AE. Hospital study of adult community requiring pneumonia. Lancet 1982; ii: 255–258. 14. Marrie T, Durant H, Yates L. Community-acquired pneumonia requiring hospitalisation: 5-year prospective study. Rev Infect Dis 1989; 11: 586–599. 15. Dean AG, Dean JA, Burton AH, Dixker RC. Epi Info, Version 5: a word processing, database, and statistics programme for epidemiology on microcomputers. USA, Georgia, Centers for Disease Control-WHO, 1990. 16. Société de Pathologie Infectieuse de Langue Française. Les infections des voies respiratoires. Méd Mal Infect 1991; 21 (Suppl.): 1–8. 17. Convention Nationale destinée à organiser les rapports entre les médecins libéraux et les caisses d'Assurance Maladie. 1994. Avenant n°1, thème n°2:7. 18. British Thoracic Society. Guidelines for the management of community-acquired pneumonia in adults admitted to hospital. Br J Hosp Med 1993; 49: 346–350. 19. Grupo de trabajo de la SEPAR. Normativa sobre diagnostic y tratamiento de las neumonias. Barcelona, Editiones Doyma, 1992. 20. Niederman MS, Bass JB, Campbell GD, et al. Guidelines for the initial management of adults with community-acquired pneumonia: diagnosis, assessment of severity, and initial antimicrobial therapy. Am Rev Respir Dis 1993; 148: 1418–1426. 21. Mandell LA, Niederman MS. The Canadian communityacquired pneumonia consensus group: antimicrobial treatment of community acquired pneumonia in adults: a conference report. Can J Infect Dis 1993; 4: 25–28. 78 H. LAURICHESSE ET AL. 22. Geslin P, Buu-Hoi A, Frémaux A, Acar JF. Antimicrobial resistance in Streptococcus pneumoniae: an epidemiological survey in France, 1970–1990. Clin Infect Dis 1992; 15: 75–98. 23. Weber M, Roussel-Delvallez M, Laurans G, et al. Enquêtes épidémiologiques régionales sur la résistance aux antibiotiques de S. pneumoniae: résultats préliminaires de 6 observatoires régionaux. Méd Mal Infect 1997; 27 (Suppl.): 7–15.
Add your comments about this article
Your username or Email:

CAPTCHA


XML     Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Altawalbeh A, Almomani T, Shatnawi M, Qawasmeh Y, Al Shbool A. Oral Cephalosporin Cefodox for treatment of out patient pneumonia in children. Int J Med Invest 2015; 4 (2) :252-256
URL: http://intjmi.com/article-1-136-en.html


Rights and permissions
Creative Commons License This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Volume 4, Issue 2 (June 2015) Back to browse issues page
International Journal of Medical Investigation
Persian site map - English site map - Created in 0.05 seconds with 37 queries by YEKTAWEB 4645